All functions |
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The DigitalDLSorter Class |
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The DigitalDLSorterDNN Class |
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The Class ProbMatrixCellTypes |
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The Class ZinbParametersModel |
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Generate bar error plots |
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Bar plot of deconvoluted cell type proportions in bulk RNA-Seq samples |
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Generate Bland-Altman agreement plots between predicted and expected cell type proportions from test data results |
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Get and set |
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Calculate evaluation metrics for bulk RNA-Seq samples from test data |
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Get and set |
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Get and set |
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Generate correlation plots between predicted and expected cell type proportions from test data |
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Create a |
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Get and set |
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Get and set |
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Deconvolute bulk gene expression samples (bulk RNA-Seq) |
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Deconvolute bulk RNA-Seq samples using a pre-trained DigitalDLSorter model |
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digitalDLSorteR: an R package to deconvolute bulk RNA-Seq samples using single-cell RNA-seq data and neural networks |
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Generate box plots or violin plots to show how the errors are distributed |
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Estimate the parameters of the ZINB-WaVE model to simulate new single-cell RNA-Seq expression profiles |
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Get and set |
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Generate training and test cell composition matrices |
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Getter function for the cell composition matrix |
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Install Python dependencies for digitalDLSorteR |
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Calculate gradients of predicted cell types/loss function with respect to input features for interpreting trained deconvolution models |
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Transform DigitalDLSorter-like list into an actual DigitalDLSorterDNN object |
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Transform DigitalDLSorterDNN-like list into an actual DigitalDLSorterDNN object |
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Load data to be deconvoluted into a DigitalDLSorter object |
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Load from an HDF5 file a trained Deep Neural Network model into a |
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Get and set |
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Get and set |
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Plot a heatmap of gradients of classes / loss function wtih respect to the input |
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Plot training history of a trained DigitalDLSorter Deep Neural Network model |
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Get and set |
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Prepare |
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Get and set |
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Get and set |
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Get and set |
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Save |
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Save a trained |
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Get and set |
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Get and set |
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Show distribution plots of the cell proportions generated by |
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Simulate training and test pseudo-bulk RNA-Seq profiles |
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Simulate new single-cell RNA-Seq expression profiles using the ZINB-WaVE model parameters |
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Get and set |
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Get and set |
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Get and set |
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Get and set |
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Get and set |
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Get top genes with largest/smallest gradients per cell type |
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Train Deep Neural Network model |
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Get and set |
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Get and set |
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Get and set |
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Get and set |